Structural Biology and Research

Structural Genetics and Genomics

Genome Informatics plays a vital role in computational biology in the development of tools for DNA sequence information and analysis, gene mapping, genetic variation, complex trait mapping, predict protein sequence and structure. The possibility of using high-throughput crystallography for defining structures of all gene products in an organism is known as structural genomics. Structures defined by these structural genomics initiatives should be useful not only as a basis for ligand design but also for homology recognition on the basis of structure–structure comparisons.