Structural Biology and Research

Determination of 3D structures

The arrangement of chemical bonds between atoms in a molecule specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond, together with any information on the geometric shape of the molecule needed to uniquely identify the type of molecule. This approach generally summarizes the usage of software tools for protein structure predictions, as a key for understanding and manipulating of its biochemical and cellular functions. This major aspect is based on computational aspects used in Bioinformatics and chemistry. Scientists use these methods to study the “native states” of the biomolecules. Some of the best methods include X-ray crystallography, Cryo-Electron Microscopy and Nuclear Magnetic Resonance.