Shu-Fang Hsu
Institute of Biological Chemistry, Academia Sinica, Taiwan
Biography
Shu-Fang Hsu has her expertise in cell biology focusing on tyrosine phosphorylation-dependent cell signaling which coordinated by protein tyrosine kinases (PTKs)
and protein tyrosine phosphatases (PTPs). PTPs comprise a superfamily of enzymes that control a diverse array of signal transduction pathways, therefore exert
their biological functions including tumorigenicity. Her current interest is crystal structure study on PTPN3-p38γ complex for structure-based drug design as an
anticancer therapy for colon cancer.
Abstract
Abstract : Hybrid methods reveal the structural architecture of PTPN3-p38 γ active-state complex