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Emmanuelle Bignon

Danish Cancer Society, Denmark

Biography

Emmanuelle Bignon is a Postdoctoral researcher working in the Computational Biology Laboratory within the Danish Cancer Society Research Center, Copenhagen,
Denmark. Her research interests focus on biochemical phenomena implicated in diseases onset and development. She uses computational chemistry tools, i.e.,
all-atom molecular dynamics, quantum calculations, QM/MM(-MD) techniques, in order to investigate reactivity and dynamical behavior of DNA and disease
related proteins. Her Postdoctoral project, supported by the Alfred Benzon Foundation, deals with redox signaling mechanisms, especially S-nitrosylation (SNO)
of cysteines, a post-translational mutation which plays an important role in cancer cells. She also investigated the structure and reactivity of damaged DNA during
her PhD obtained in June 2017.

Abstract

Abstract : Towards an accurate description of the S-nitrosylated cysteine by classical molecular simulations: implications for the study of cancer related SNO-proteins