John B. Bruning
The University of Adelaide, Australia
Biography
I received by BSc from Texas A&M University in 1997. I began crystallography in the laboratory of Yousif Shamoo at Rice University. During my graduate studies I worked on the structural mechanism of the human sliding clamp and its interactions with DNA replication proteins. I received my PhD in 2005. I completed 2 successful post-docs. The first was at the Scripps Research Institute from 2005-2007 working on structural studies of nuclear receptors including PPAR, RXR, ER, and TR. My second post-doc was with Jim Sacchettini in the Houston Medical centre and I was a part of the TB structural genomics consortium. I received my first faculty position at the University of Adelaide in 2012 as a lecturer. I was tenured in 2015 and promoted to Senior Lecturer in 2016. Do to my continued collaboration with Scripps, I was also appointed adjunct professor of the Scripps Research Institute in 2016.
Abstract
Abstract : Structural mechanism of partial agonists and antagonists of PPARgamma for use as antidiabetics