Hagen Hofmann
Weizmann Institute of Science, Israel
Biography
Hagen Hofmann received his PhD from the Martin-Luther University Halle-Wittenberg (Germany) in 2008. In the period 2008 - 2014, he was a postdoctoral fellow at the University of Zurich in the group of Benjamin Schuler and since 2014 he is heading the “Molecular Systems Biophysics” group at the Weizmann Institute of Science (Israel). He and his group use a broad set of single-molecule fluorescence tools to understand the dynamics of proteins and protein networks on timescales from nanoseconds to hours. In addition, live-cell imaging, in vivo single-molecule FRET, and single particle tracking is used to monitor proteins in live cells. His interest ranges from the physics of disordered proteins over coupled binding and folding reactions up to stochastic genetic circuits and regulatory protein networks.
Abstract
Abstract : Slow domain reconfiguration causes power law kinetics in a two-state enzyme