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Christina Scharnagl


Christina Scharnagl

Technical University of Munich, Germany

Biography

Christina Scharnagl has her expertise in molecular dynamic simulations of membrane proteins. Her work focuses on biophysical principles of the interdependence of transmembrane helix dynamics, helix-helix binding, and helix-lipid interactions. In silico modelling and advanced computational analysis are closely connected to experimental work in research collaborations in order to interpret and guide the experiments and to validate the simulations. The aim of the joint efforts is to understand the impact of these phenomena on multiple biological processes, such as membrane fusion and intramembrane proteolysis. 

Abstract

Abstract : Does the dynamics of their transmembrane domain qualify bitopic membrane proteins as substrates for intramembrane proteolysis?