Wladek Minor
University of Virginia, USA
Title: The impact of reproducibility on structure based drug discovery
Biography
Biography: Wladek Minor
Abstract
The drug discovery process depends on the veracity of every decision point on the path from initial experiments to FDA
approval, and erroneous data collected along the path can waste valuable time and resources. Th e presentation will discuss the
sources of uncertainty that aff ect the drug discovery process, focusing on factors that impact structure based drug design the most.
Th e selection of structures used as the basis of computations or data mining will be discussed in detail. All aspects of procedures
essential for structural validation and best practices for data management of all experimental steps will be also discussed