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Igor Sokolov

Tufts University, USA

Title: Quantitative and repeatable measurements of elastic moduli of cells

Biography

Biography: Igor Sokolov

Abstract

Mechanics of eukaryotic cells at the nanoscale is a challenging problem due to complexity of cells. Besides fundamental
interest, such measurements are important because it has been demonstrated that the elastic modulus of cells can
correlate with various diseases and even aging. Atomic force microscopy (AFM) is the technique of use. At the same time, there
is a lot of confusion in the process of measurements of the elastic modulus of cells. In the talk, author will present the modern
overview of the topic, describe step-by-step how to do the measurements of the elastic modulus in quantitative manner that is
independent of the particular microscope, AFM probe, and mechanical model.